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Symbol Name ID |
Mettl3
methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit MGI:1927165 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | reproductive system phenotype |
abnormal oocyte morphology |
decreased oocyte number |
oligozoospermia |
abnormal male germ cell morphology |
abnormal spermatogonia morphology |
decreased male germ cell number |
abnormal male germ cell physiology |
abnormal ovary morphology |
abnormal seminiferous tubule epithelium morphology |
seminiferous tubule degeneration |
small testis |
testis degeneration |
abnormal female meiosis |
female infertility |
male infertility |
reduced male fertility |
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| Availability | Mouse Genotype | |||||||||||||||||
| Mettl3em1Chhe/Mettl3em1Chhe Tg(Ddx4-cre)1Dcas/0 (conditional) |
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| Mettl3em1Chhe/Mettl3em1Chhe Stra8em1(GFP/cre)Smoc/Stra8+ (conditional) |
* | |||||||||||||||||
| Mettl3tm1.1Jhha/Mettl3tm1.1Jhha Tg(Ddx4-cre)1Dcas/0 (conditional) |
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| Mettl3tm1.1Jhha/Mettl3tm1.1Jhha Tg(Stra8-icre)1Reb/0 (conditional) |
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| Mettl3tm1.1Jhha/Mettl3tm1.1Jhha Tg(Prm-cre)58Og/0 (conditional) |
* | |||||||||||||||||
| Mettl3tm1.1Jhha/Mettl3tm1.1Jhha Tg(Zp3-cre)93Knw/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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